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Clinical data highlights its role in Phase II liver detoxification, binding to toxins so they can be excreted

This hormone helps regulate appetite, blood sugar levels, and digestion

The hallmark structural feature of GLP-1R and other Class B GPCRs is a large N-terminal extracellular domain (ECD)

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(Sartain, 2024) A study found that tapering patients off of semaglutide over a course of 9 weeks while being coached on diet and exercise led to sustainable weight management after being off of the medication for 26 weeks