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It is a lab-created peptide designed to mimic and enhance the actions of naturally occurring hormones like GLP-1, GIP, and glucagon

Short-acting GLP-1 receptor agonists include immediate-release exenatide (Byetta) with a half-life of approximately 2.4 hours

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Retatrutide skin sensitivity is a reported side effect that occurs in roughly 7% of people using this triple-agonist injectable

The GIP pathway is particularly important for patients whose weight challenges involve metabolic inefficiency or insulin resistance