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Limit: weight regain is faster upon drug discontinuation than after surgery, and cumulative chronic treatment cost may equal or exceed surgery at 5-7 years

Lipohypertrophy is a buildup of thickened or lumpy fatty tissue under the skin from repeated injections in the same spot

Furthermore, a national cohort study found that a notable percentage of patients (up to 10%) required revisional surgery within 5 years of follow-up [16]

Zepbound Segment: Significantly Growing By product, the Zepbound segment is predicted to witness significant growth in the market over the forecast period

These evidences all suggest that the action of GLP-1R in liver cells may be directly stimulated by ligand-receptor action

Lancet Diabetes Endocrinol 6(8):605617