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25 , 9498 (2016) Gutman, M., Couillard, S., Labrie, F., Candas, B., Labrie, C.: Effects of the antiestrogen em-800 (SCH 57050) and cyclophosphamide alone and in combination on growth of human zr-75-1 breast cancer xenografts in nude mice

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NMR Structural Resolution of FOXO4-DRI/p53TAD2 Complex (Nature Communications, 2025) Disordered-to-Ordered Complex Formation: Structural Basis of FOXO4-DRIs Senolytic Mechanism A landmark structural study published in Nature Communications (2025) resolved the solution NMR structural models of the p53 transactivation domain (TAD2) in complex with the FOXO4 forkhead domain and with FOXO4-DRI