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GIP is secreted by the enteroendocrine K-cells concentrated in the proximal intestines, including the duodenum and jejunum ( via both neural and endocrine mediated factors ( Incretins act on G-protein coupled receptors on the beta cells of the pancreas, leading to a cAMP mediated pathway that ultimately results in insulin secretion ( Figure 1 )
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Fermentable fiber is fermented by gut bacteria into short-chain fatty acids, which in turn stimulate GLP-1 secretion
Each biochemical value was normalised to cell number and scaled to its median value
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