Proc Soc Exp Biol Med 214(3):242247 Smith IJ, Dodd SL (2007) Calpain activation causes a proteasome-dependent increase in protein degradation and inhibits the Akt signalling pathway in rat diaphragm muscle
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Key Takeaway: Prior authorization for weight-loss GLP-1s usually requires a documented BMI of 30 or higher, or 27 with comorbidities, plus a 6-month lifestyle intervention history
NNT measures have great clinical relevance and have been increasingly used in health economic evaluations related to diabetes [31,32,33,34,35]
Tatsuta Y, Kasai K, Maruyama C, et al