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LP3-R is used in controlled laboratory environments to study dual and triple receptor interactions and downstream signaling mechanisms

Other pipeline medications like CagriSema (semaglutide plus cagrilintide), survodutide , and orforglipron (an oral GLP-1) continue to push the boundaries of what pharmacological weight loss can achieve

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Photo Credit: Adam Fisher, Baldwin Publishing 185 mins This lighter version of pot pie delivers creamy, comforting taste without overdoing it

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According to NHS England, those eligible will have: a BMI of 40 or over (or 37.5 if from a minority ethnic background) and four out of five of the following conditions: type 2 diabetes, high blood pressure, heart and vascular disease, high cholesterol and obstructive sleep apnoea Follow Northamptonshire news on BBC Sounds , Facebook , Instagram and X .