New Patient Pricing Individual Initial Program: $149 Includes your first two consultations and first two rounds of lab work
Insulating Mid-Layers: Fleece or down vests are excellent for keeping your core warm without being overly bulky
Gosselin NH
certificate of analysis available on request Research Applications Suitable Laboratory Uses for FOXO4-DRI FOXO4-p53 protein-protein interaction disruption assays CO-IP, competitive binding, and proximity ligation studies Selective senescent cell apoptosis induction SA--gal, p16, p21, p53 marker-confirmed senescent populations p53 TAD2 binding, phospho-p53 (Ser15) nuclear exclusion, and mitochondrial translocation pathway studies BAX/BCL-2/Caspase-3 intrinsic apoptosis cascade investigations in senescent cell models SASP characterisation and suppression IL-6, IL-8, MMP, VEGF, CXCL2/3 secretome studies Tissue-specific senescence models fibroblasts, endothelial cells, Leydig cells, chondrocytes, keloid fibroblasts Vascular ageing pathway research endothelial senescence, aortic function, and ROS pathway studies Senescent cancer cell biology and drug resistance pathway research Comparative senolytic research FOXO4-DRI vs
Downie 1991
ArticlePubMedPMC 28