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The American Diabetes Association upgraded GLP-1 agonists to preferred second-line agents for patients with cardiovascular comorbidities in its 2024 Standards of Care, elevating the drug class above sulfonylureas and DPP-4 inhibitors for many clinical scenarios

Melanotan II Melanotan II is a synthetic analog of alpha-melanocyte-stimulating hormone (-MSH), developed to explore its effects on melanogenesis, sexual function, and energy metabolism

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At moderate doses (8 mg weekly), GI issues increased but were offset by significantly improved weight loss results

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