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Int J Mol Sci (2019) 20:904

To construct expression vectors for the secretion of Exe4, double-stranded DNAs of Exe4 fused with signal peptides (SPs) and furin-cleavable sequences were synthesized (Azenta) and inserted into a CAG promoter-containing pCAG backbone vector using the In-Fusion HD cloning kit (Takara Bio)

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As of May 1, 2024, there were 87 active lawsuits within the MDL, with potential growth to several thousand cases due to the drugs widespread usage

doi: 10.3390/cells10030571 302 WilliamsJ