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These findings suggest that although WD increased body weight and GE2 improved associative learning in both sexes, both WD and GE2 had differential affects on metabolic hormones, insulin regulation, inflammation and neuroplasticity

This transition can be especially challenging because pregnancy itself becomes progressively insulin-resistant as placental hormones rise

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In addition to signaling the pancreas to release insulin to manage blood sugar after meals, it also reduces glucagon to prevent excess glucose production