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In particular, we need to support our livers Phase II detoxification pathway to ensure toxins released from our bodys fat storage in Phase I are not released and recycled, adding to our livers already toxic load

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If confirmed in Phase III, elecoglipron could offer an additional oral GLP1 option for patients and clinicians seeking alternatives to injectable regimens. Beyond efficacy trials, AstraZenecas Appendix highlights an extensive supporting programme for elecoglipron, including Phase I studies in healthy volunteers, renal and hepatic impairment, bioavailability, and key drugdrug interaction assessments