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This suggests that the current recommendation for vitamin B12 is likely not high enough

Dosage Adjustments Based on Clinical Response Adjusting the dosage is a big part of treating vitamin B12 deficiency

Trade-offs: The benzyl alcohol contraindicates use in neonates (documented in Pfizer prescribing information neonatal gasping syndrome was the historic concern)

(Thats why vitamin B12 is often treated with B12 injections fewer barriers to absorption!) A different small study on people who underwent gastric bypass surgery found that higher doses of oral B12 supplements (1,000 to 2,000 mcg) are about as effective as injections

How Many B12 Pills Equal a Shot