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Cagrilintide is engineered to provide prolonged receptor activation compared to native amylin

When mitochondrial damage occurs, PINK1 accumulates on the mitochondrial outer membrane and recruits the E3 ubiquitin ligase Parkin (Picca et al., 2023)

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however, reactive oxygen species (ROS) continue to be an important factor in the course of this disease [2,3,4,8]

The reconstituted solution may be refrigerated and stored for up to 4 hours

PMID: 33290831