They are both usually administered as weekly injections
By activating this pathway, retatrutide helps smaller portions feel sufficient, curbs snacking urges and keeps energy levels steady throughout the day
Interest in these medications has recently accelerated, largely for their weight-loss effects, although access to and use of GLP-1 RA medications may be impacted by high cost, limited insurance coverage for patients without T2D and medication shortages
For example, chronic treatment with MK-801 promotes hyperthermia and hyperlocomotion 15,16,17
Lifestyle interventions remain the cornerstone of obesity management, and typically involve a multidisciplinary approach with GPs, cardiologists, endocrinologists and allied health professionals
[8] Anyone experiencing these symptoms should stop use immediately and seek urgent medical attention