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The two medications are metabolised through different pathwayssemaglutide is broken down by proteolytic enzymes similar to endogenous proteins, whilst ibuprofen undergoes hepatic metabolismmeaning they do not compete for the same metabolic processes

The move comes amid growing concerns over compounded versions of GLP-1 drugs like semaglutide and tirzepatide, which are often used for type 2 diabetes and weight management but are not FDA-approved in their compounded forms

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Badulescu Sebastian T, Le Aniqa G, Han, et al

The drugs, which include Wegovy, Mounjaro, and Victoza, are used to treat diabetes, since they help generate insulin