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In addition to immunotherapy, the development of CSC-specific nanomedicine is another area of growing interest

Injectable administration is hypothesized to provide systemic distribution, but human pharmacokinetic data for this route does not exist

SLC1A5 is highly expressed in diverse solid tumors, including triple-negative breast cancer (TNBC) [32], KRAS-mutated colorectal cancer (CRC) [33], esophageal cancer [30], gastric cancer [34], lung cancer [35], ovarian cancer [36], prostate cancer [37], renal cell [38], head and neck squamous cell carcinoma (HNSCC) [39] and hepatocellular carcinoma [40]

This is not only a regulatory and consumer preference consideration