[3] Traverso N, Ricciarelli R, Nitti M, et al
1999, Chapman and Hall, New York, Ch 59- Frei B, Traber M: The new US dietary reference for vitamins C and E
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ELIXA trial included patients with recent cardiovascular event (patients with acute coronary syndrome 180 days before randomization), and although there was no benefit in MACE reduction in lixisenatide treated patients compared to placebo, results revealed cardiovascular safety of lixisenatide in this specific high risk population (38, 40)
Growth factor expression related to repair processes
Apparently the factors that lower the enzymatic degradation and metabolism of a peptide tend to stabilize the peptide 48,49