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These findings highlight the emerging concept of combining appetite-modulating therapies with muscle-preserving mechanisms to optimize body composition in obesity treatment

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This activation enhances insulin sensitivity, allowing cells to utilize glucose more efficiently and lowering blood sugar levels

For example, semaglutide induces weight losses greater than 15% in 60% of those treated, and nearly 40% even lost more than 20% of their initial body weight (Figure 6A)

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