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By the late 1970s admissions to hospital and the workload of gastric surgeons had begun to decline as a result of the introduction of H2 receptor agonists, a new class of drugs that block the action of histamine

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2.11 Mitochondrial morphological analysis by confocal microscopy A375 human melanoma cells were seeded in a 4-chamber plate at a density of 1.5 10 4 cells/well in 500 l culture medium in a 5% CO 2 incubator overnight at 37 C