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International Journal of Molecular Sciences , 19(7), 2102

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 7% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

The peptide is created by adding 13 amino acids to the N-terminal end of IGF-1 and by converting the glutamic acid at position 3 of IGF-1 to an arginine residue

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The glutathione group reported 58% lower hangover severity scores the following morning compared to placebo, with the most pronounced differences in nausea (72%) and headache intensity (64%)