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Unlike GLP-1, GIP also promotes GCG release in a glucose-dependent way

But it's also possible that GLP-1s can have a direct impact on the brain, Jari Tiihonen, MD, PhD, professor in the Department of Clinical Neuroscience at Karolinska Institutet, tells SELF

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However, clinical evidence consistently shows that combining medication with lifestyle modifications produces superior long-term outcomes compared to medication alone

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