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Reported side effects include mild skin irritation and redness

L-Cysteine supplementation lowers blood glucose, glycated hemoglobin, CRP, MCP-1, and oxidative stress and inhibits NF-B activation in the livers of Zucker diabetic rats

J Clin Endocrinol Metab 90:39893994 Mller J, Jrgensen JO, Marqversen J, Frandsen E, Christiansen JS (2000) Insulin-like growth factor I administration induces fluid and sodium retention in healthy adults: possible involvement of renin and atrial natriuretic factor

These results demonstrated that diosgenin attenuates diabetic cognitive dysfunction in methylglyoxal-treated PC12 cells in a dose-dependent manner