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These include severe chest pain, sudden shortness of breath, signs of stroke such as sudden weakness or slurred speech, uncontrolled bleeding, sudden severe abdominal pain, or symptoms of severe allergic reaction like difficulty breathing and throat swelling

Studies have identified that autophagy deficiency leads to NRF2 activation due to p62 accumulation [83]

Kim, J., Samaranayake, M

Glutathione S -transferase catalyzes the isomerization of ( R )-2-hydroxymenthofuran to mintlactones

Although the pathogenetic role of oxidative stress in these diseases is well established, there is still limited evidence on the therapeutic role of GSH in such conditions

This study found that N-acetylaspartate (NAA)/total creatine (tCr) and choline (Cho)/tCr levels changed in a time-phase-dependent manner in migraine ( Oxidative stress and antioxidant defense in migraine A study using a migraine rat model revealed increased malondialdehyde levels in the cortex and trigeminal ganglion, along with pro-injurious effects of reactive oxygen species (ROS) on the brain via transient receptor potential A1 (16)