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In contrast, viral hepatitis is the most common cause in developing countries

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Both responses correlated with GSH redox changes, with diamide increasing GSSG, and hydrogen peroxide inducing protein-GSH mixed disulfides (GSSR)

For instance, researchers have observed activation of the ferroptosis process in a mouse model of Epilepsy-associated cognitive disorder (ECD), and inhibition of ferroptosis through pharmacological intervention or genetic manipulation targeting Lox can ameliorate ECD-related damage

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