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So even though Im personally not a huge fan of using bicarbonates as alkalizers, theoretically, if you took a bicarbonate alkalizer it is possible that you may increase the availability of sulfur molecules and thus GAGs and sulfated mucins, which will improve gut integrity, reduce food reactions, etc

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Gastroenterology 2020;158:930-946.e1

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Vet Pathol 58:1033

Elevated intracellular calcium concentrations, in turn, appear to prompt the secretory vesicles inside these cells to release growth hormone into the bloodstream