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Patients with a history of pancreatitis, particularly those with chronic pancreatitis or recurrent acute episodes, may be at increased risk for pancreatitis exacerbation

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As such, it is important to remind patients to rotate their injection site and use a new needle/pen needle for each injection to avoid lipohypertrophy

Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice

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