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The next to come down the track is tirzepatide (Eli Lilly), which studies suggest has an even more impressive impact on weight loss[6]

However, delayed gastric motility becomes a safety concern during surgery because it increases the risk of aspiration, a condition where stomach contents enter the airway during anesthesia

Direct answer: Oral GLP-1 options now exist, but they do not contain tirzepatide

Another key question is whether psychiatric effects are direct or secondary to metabolic improvements

Stepwise dose escalation was also applied in the phase 2 and 3 trials with oral semaglutide, leading to fewer events of nausea [15,16,17,18,19]