Polyendocrine metabolic ovarian syndrome isnt yet an official FDA indication for any GLP-1 medications, but clinicians are increasingly using the drugs for women with the condition, which is closely tied to insulin resistance and weight
The warnings were based on worrying signs when the drug was given to pregnant animals, Belluz said, but the FDA believes the side effects currently seen are more likely attributable to weight loss than the drug itself
Most patients begin at low doses (0.25 mg weekly) and advance over 48 weeks to maintenance doses (0.52.4 mg weekly)
Warnings: It should be used under medical supervision, particularly in patients with a history of pancreatitis, thyroid cancer, or severe gastrointestinal conditions
All estimates assume current drug prices
Less frequent dosing could help more people stick with long-term weight control programs