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Renal cells in the context of ADPKD exhibit a wide range of metabolic abnormalities, including the decreased expression of system Xc- and reduced activity of GPX4, which are the necessary conditions and typical characteristics of ferroptosis [252, 253]

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After performing an intragroup analysis, no changes were observed at any time points or in either groups, whatever the lipid biomarker monitored (total cholesterol, HDL-C, LDL-C, TG)

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McRorie 2015)