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Preclinical studies have confirmed that in the PA-induced L6 cell muscular atrophy model, liragutide plays a key role in promoting autophagy through the SESN2-mediated AMPK/Akt/mTORC1 pathway

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In the study, AD109 led to dose-dependent decreases in the placebo-adjusted change from baseline in the primary endpoint of apneahypopnea index (AHI)